Carbamazepine (Tegretol) can cause neural tube defects. Give
_____ to women of childbearing age
folic acid
Carbamazepine (Tegretol) can decrease blood concentrations of
_______.
oral contraceptives
absolutely never give Carbamazepine (Tegretol) with
MAOIs
When used in a combo with Depakote, ______ Trileptal dose.
decrease
Carbamazepine (Tegretol) may ______ total serum cholesterol,
especially HDL
increase
Carbamazepine (Tegretol)- give patients with _______ disease
1/3-1/2 of the regular dose.
hepatic
Carbamazepine (Tegretol) lab monitoring- CBC every ____
weeks for the first _____ months. _____ and _____ tests
quarterly.
2, 2, liver, renal
Lamictal stabilizes mood from
,below
Lamictal maximally impacts the ______ component of bipolar
disorders
depressive
Lamictal prolongs the time between episodes of depression &
mania but is more effective in lengthening the intervals between
_____ episodes. Effecftive as treatment for _______ bipolar
disorder
depressive, rapid-cycling
This med is known for its absence of weight gain and sedation
Lamictal
DO not give Lamictal if under ____ y/o
16
Most serious side effect of Lamictal
rash
If pts miss more than ____ consective days of Lamcital restart at
lowest dose
4
Most serious drug interaction with Lamictal is _____. ______
also increases plasma concentrations but to a lesser extent.
depakote, zoloft
Topiramate (Topamax) is an anticonvulsant used as adjunctive
therapy for _____. Combined with bupropion to treat _____
,bpad, obesity
Topiramate (Topamax) enhances ____ function. Blocks VSSC
and is an antagonist to glutamate. Anhydrase inhibitor- ______
sodium bicarb
GABA, increases
Topiramate (Topamax) with renal insufficiency requires _____
dose.
decreased
Educate patients on Topiramate (Topamax) to
drink fluids
When Topiramate (Topamax) is combined with Depakote
______ dose.,
decrease
Topiramate (Topamax) titrate gradually to 200 mg BID over ___
weeks
8
Give Topiramate (Topamax) at
night
Topiramate (Topamax) can affect _____ balance, cause
arrhythmias, and renal calculi
acid base
Gabapentin/Pregabalin (Anticonvulsants) are excreted in the
urine
, Gabapentin/Pregabalin effectiveness is decreased with
antacids
Gabapentin dosing: Day 1 ___ mg, day 2 ____ mg, Day 3 ____
mg to a max of _______. Taper with d/c
300, 600, 900, 1800
Levitiraceptam (Keppra) is used to treat _____ and anxiety and
to augment ______ drug therapy
mania, antidepressant
Levitiraceptam (Keppra) side effects: some patients may
experience behavioral disturbances and _____ may occur.
Suicidal pts may become agitated.
hallucinations
Levitiraceptam (Keppra) doses should be decreased in pts with
impaired ____ function
renal
Zonisamide (Zonegran) is used to treat
mania
Zonisamide (Zonegran) can cause fatal side effects such as:
blood dyscrasias and rash
Zonisamide (Zonegran) causes weight ____
loss
Zonisamide (Zonegran) works by blocking ______ channels