UTMB 5355 ADVANCED PATHOPHYSIOLOGY EXAM 2,
3 & 4 NEWEST 2025 PACKAGE DEAL| 3 LATEST
VERSIONS WITH COMPLETE REAL EXAM QUESTIONS
AND CORRECT DETAILED ANSWERS (VERIFIED
ANSWERS) ALREADY GRADED A+| BRAND NEW!!
Biogenic Amine Theory linked to depression .....ANSWER.....
Deficiency of neurotransmitters in brain of norepinephrine,
dopamine, and/or serotonin. Particularly, a decrease in receptor
binding with serotonin.
Neurotransmitter Receptor Hypothesis linked to depression
.....ANSWER..... A deficiency of monoamine neurotransmitters at
neuronal synapses.
Antidepressants increase .....ANSWER..... Neuronal synaptic levels
of monoamine neurotransmitters.
,Page 2 of 33
if you have more receptors than neurotransmitters .....ANSWER.....
Neurotransmitters do not have time to re-charge thus, they do not
function properly.
Hypothalamic-Pituitary-Adrenal (HPA) System Dysregulation
.....ANSWER..... HPA system dysregulation with excessive
glucocorticoid secretion is found in a large percentage of people
suffering from major depression.
Patho of Alzheimer's includes - plaque formation, presence of --,
with decreased levels of - .....ANSWER..... Amyloid B,
neurofibrillary tangles, acetylcholine these disrupt impulse
transmission
neurofibrillary tangles .....ANSWER..... are a deformation of the
structure that carries nutrients to neurons of the brain.
Decreased levels of choline acetyl transferase and acetylcholine
is associated with .....ANSWER..... Memory loss
,Page 3 of 33
Most common cause of dementia .....ANSWER..... Alzheimer's
disease fatal 5-10 years
Characteristics of Alzheimer's .....ANSWER..... Loss of memory,
language , inability to learn new things, dysfunction, delusions,
cannot perform ADLs, majorly effects social life
Parkinson's Disease is .....ANSWER..... Chronic motor progressive
neuro-degenerative known as a shaking palsy
Parkinson's disease is associated with .....ANSWER..... basal
ganglia dysfunction and atrophy of neurons in the substantia
nigra that produce dopamine;
Characteristics of Parkinson's disease .....ANSWER..... Tremors at
rest, rigidity, bradykinesia, muscular rigidity and postural
abnormalities.
2 Main Categories of CVA .....ANSWER..... Hemorrhagic and
Ischemic
, Page 4 of 33
Hemorrhagic CVA .....ANSWER..... Blood produces inflammatory
reaction, swelling, displaces brain tissue and increases ICP
2 types of hemorrhagic stroke .....ANSWER..... Intracerebral and
subarachnoid
Intracerebral Hemorrhage .....ANSWER..... Blood vessel leaks
directly into brain tissue
Subarachnoid hemorrhage .....ANSWER..... Bleeding into the
subarachnoid space, caused by trauma, aneurysm rupture
presents as "worst headache of life". surgical emergency
Ischemic CVA .....ANSWER..... reduction in cerebral blood flow
results in hypoxia and irreversible cell death with associated
cerebral edema
3 types of ischemic CVA .....ANSWER..... thrombotic, embolic,
hypercoagulable states.