Clayton’s Basic Pharmacology for Nurses 20th Edition by Michelle J. Willihnganz
MS RN CNE, Samuel L. Gurevitz PharmD (2025) || ALL CHAPTERS|| GRANTEE A+
20th Edition
,table of contents
unit i: introduction to pharmacology ........................................................ 4
chapter 01: basic principles of pharmacology ............................................................................ 4
chapter 02: drug actions across the life span ........................................................................... 15
chapter 03: the nursing process and pharmacology ................................................................ 27
chapter 04: patient education to promote health .................................................................... 39
unit ii: medication administration .......................................................... 48
chapter 05: principles of medication administration and medication safety ........................... 48
chapter 06: percutaneous administration ................................................................................ 60
chapter 07: enteral administration ........................................................................................... 71
chapter 08: parenteral administration: safe preparation ......................................................... 81
chapter 09: parenteral administration: intradermal, subcutaneous, and intramuscular ......... 90
chapter 10: parenteral administration: intravenous ............................................................... 100
unit iii: drugs affecting neurologic disorders ...................................... 112
chapter 11: drugs affecting the central and peripheral nervous system ................................ 112
chapter 12: drugs used to treat neurodegenerative disorders ............................................... 125
chapter 13: drugs used to treat seizure disorders .................................................................. 134
chapter 14: drugs used to treat headaches ............................................................................ 145
chapter 15: drugs used to treat pain: focus on opioids .......................................................... 156
unit iv: drugs affecting psychiatric disorders ...................................... 168
chapter 16: drugs used to treat attention deficit hyperactivity disorder .............................. 168
chapter 17: drugs used to treat substance use disorders ...................................................... 178
chapter 18: drugs used to treat schizophrenia ...................................................................... 188
chapter 19: drugs used for depressive and bipolar disorders ................................................ 199
chapter 20: drugs used for anxiety disorders ......................................................................... 213
chapter 21: drugs used to treat sleep disorders ..................................................................... 223
unit v: drugs affecting cardiovascular disorders ................................. 232
chapter 22: drugs used to treat dyslipidemias ....................................................................... 233
chapter 23: drugs used to treat hypertension ........................................................................ 243
, chapter 24: drugs used to treat dysrhythmias ........................................................................ 258
chapter 25: drugs used to treat angina pectoris..................................................................... 267
chapter 26: drugs used to treat peripheral vascular disease.................................................. 280
chapter 27: drugs used to treat thromboembolic disorders .................................................. 288
chapter 28: drugs used to treat heart failure ......................................................................... 300
unit vi: drugs affecting the respiratory system ................................... 313
chapter 29: drugs used to treat upper respiratory disease .................................................... 313
chapter 30: drugs used to treat lower respiratory disease..................................................... 326
unit vii: drugs affecting the digestive system ..................................... 344
chapter 31: drugs used to treat gastroesophageal reflux and peptic ulcer disease ............... 344
chapter 32: drugs used to treat nausea and vomiting ............................................................ 357
chapter 33: drugs used to treat constipation and diarrhea .................................................... 369
unit viii: drugs affecting the endocrine system ................................... 382
chapter 34: drugs used to treat diabetes mellitus .................................................................. 382
chapter 35: drugs used to treat thyroid disease ..................................................................... 397
unit ix: drugs affecting the reproductive system ................................ 409
chapter 36: drugs used in obstetrics ....................................................................................... 409
chapter 37: drugs used in men’s and women’s health ........................................................... 421
unit x: drugs affecting other body systems ......................................... 434
chapter 38: drugs used to treat disorders of the urinary system ........................................... 435
chapter 39: drugs used to treat glaucoma and other eye disorders ...................................... 447
chapter 40: drugs used to treat cancer ................................................................................... 459
chapter 41: drugs used to treat the musculoskeletal system ................................................. 472
chapter 42: drugs used to treat immune and inflammatory disorders ................................. 485
unit xi: drugs used to treat infections .................................................. 494
chapter 43: drugs used to treat bacterial infections............................................................... 494
chapter 44: drugs used to treat viral infections ..................................................................... 508
chapter 45: drugs used to treat fungal infections................................................................... 518
, Unit i: introduction to pharmacology
Chapter 01: basic principles of pharmacology
Multiple choice
1. Which priority action should be implemented when hives are assessed on a patient
started on a new medication?
A. Notify physician of allergic reaction.
B. Notify physician of idiosyncratic reaction.
C. Notify physician of potential teratogenicity.
D. Notify physician of potential tolerance.
Accurate Answer: a
An allergic reaction is indicative of hypersensitivity and manifests with hives and/or urticaria,
which are easily identified. An idiosyncratic reaction occurs when something unusual or
abnormal happens when a drug is first administered. A teratogenic reaction refers to the
occurrence of birth defects related to administration of the drug. Tolerance refers to the body‘s
requirement for increasing dosages to achieve the same effects that a lower dose once did.
Dif: cognitive level: application ref: p. 17 obj: 4
Nat: nclex client needs category: physiological integrity
Top: nursing process step: assessment con: clinical judgment | safety
2. The nurse administers an initial dose of a steroid to a patient with asthma. Thirty
minutes after administration, the nurse finds the patient agitated and stating that everyone is
out to get me. Which term is used for this unusual reaction?
A. Desired action
B. Adverse effect
C. Idiosyncratic reaction
D. Allergic reaction
Accurate Answer: c