age 1 of 30
AG-ACNP Endocrine Actual Exam 2025/2026
Questions with Verified Solutions || Already Graded
A+ <Recent Version>
What is the pathology of diabetes mellitus?
.......Answer.........Metabolic disease resulting from a breakdown
in the body's ability to produce or utilize insulin causing
hyperglycemia.
Explain the pathology of DM Type 1. .......Answer.........Insulin
DEPENDENT. Total destruction of beta cells.
Islet cell antibodies - 90% of patients
Ketone development occurs
What are the signs and symptoms of DM Type I?
.......Answer.........Polyphagia
,age 2 of 30
Polydypsia
Polyuria
Weight loss
What are the labs/diagnostics indicative of DM Type I?
.......Answer.........Random BG - > 200 mg/dL
Fasting BG - > 126 mg/dL x 2 separate occasions
HgbA1c - routine diagnostic; > 7%
BUN/Cr elevated due to dehydration
Ketonemia, ketonuria
What pharmacological therapy is indicated if the patient
presents with ketones and DM Type I? Dose?
.......Answer.........Insulin therapy.
, age 3 of 30
TDD - 0.5 units/kg/day
2/3 TDD in am and 1/3 in pm
What is the Conventional Split Dose Mixtures for insulin
administration? .......Answer.........Morning dose of insulin - 2/3
NPH, 1/3 Regular
Evening dose of insulin - 1/2 NPH, 1/2 Regular
Identify the three Insulin Analogs. .......Answer.........Aspart
(NovoLog)
Glargine (Lantus) - prolonged duration
Lispro (Humalog) - rapid onset
What is the pathology of DM Type II?
.......Answer.........Circulating insulin is not enough to meet patient's
AG-ACNP Endocrine Actual Exam 2025/2026
Questions with Verified Solutions || Already Graded
A+ <Recent Version>
What is the pathology of diabetes mellitus?
.......Answer.........Metabolic disease resulting from a breakdown
in the body's ability to produce or utilize insulin causing
hyperglycemia.
Explain the pathology of DM Type 1. .......Answer.........Insulin
DEPENDENT. Total destruction of beta cells.
Islet cell antibodies - 90% of patients
Ketone development occurs
What are the signs and symptoms of DM Type I?
.......Answer.........Polyphagia
,age 2 of 30
Polydypsia
Polyuria
Weight loss
What are the labs/diagnostics indicative of DM Type I?
.......Answer.........Random BG - > 200 mg/dL
Fasting BG - > 126 mg/dL x 2 separate occasions
HgbA1c - routine diagnostic; > 7%
BUN/Cr elevated due to dehydration
Ketonemia, ketonuria
What pharmacological therapy is indicated if the patient
presents with ketones and DM Type I? Dose?
.......Answer.........Insulin therapy.
, age 3 of 30
TDD - 0.5 units/kg/day
2/3 TDD in am and 1/3 in pm
What is the Conventional Split Dose Mixtures for insulin
administration? .......Answer.........Morning dose of insulin - 2/3
NPH, 1/3 Regular
Evening dose of insulin - 1/2 NPH, 1/2 Regular
Identify the three Insulin Analogs. .......Answer.........Aspart
(NovoLog)
Glargine (Lantus) - prolonged duration
Lispro (Humalog) - rapid onset
What is the pathology of DM Type II?
.......Answer.........Circulating insulin is not enough to meet patient's
