AG-ACNP GI Actual Exam 2025/2026 Questions with
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Which medications cause peptic ulcer disease?
.......Answer.........NSAIDS
ASA
What are the expected physical findings associated with PUD?
.......Answer.........Physical exam unremarkable
GI bleeding - melena, hematemesis or coffee-ground emesis
(duodenum)
In a patient presenting with coffee-ground emesis, where does
the ACNP suspect the ulcer is located? .......Answer.........In the
duodenum
,age 2 of 35
What are the signs and symptoms of a perforated peptic ulcer?
.......Answer.........Severe epigastric pain
BOARD LIKE abdomen
QUIET BOWEL SOUNDS
Acute abdomen
What is the first-line treatment in PUD? .......Answer.........H2
Blocker - Ranitidine (Zantac) 300 mg/hr at SLEEP
Famotidine (Pepcid) 40 mg/hrs at SLEEP
When should you educate patients on administration of a Proton
Pump Inhibitor? .......Answer.........Patient should take PPI 30
minutes before meals
,age 3 of 35
What is the BBW associated with PPIs? .......Answer.........HIP
FRACTURE
Glucocorticoids
At what age do duodenal ulcers typically present?
.......Answer.........30-55 yo.
At what age do gastric ulcers typically present?
.......Answer.........55-65 years old
What are the signs and symptoms associated with a duodenal
ulcer? .......Answer.........Gnawing, epigastric pain
Relief of pain WITH eating
What are the signs and symptoms associated with a gastric
ulcer? .......Answer.........Gnawing, epigastric pain
, age 4 of 35
Pain WORSENS with eating
What is the dosing for PPIs in PUD?
.......Answer.........Pantoprazole (Protonix) 40 mg/day
Omeprazole (Prilosec) 20 mg/day
What patient education is needed when prescribing Mucosal
Protective Agents? .......Answer.........Sucralfate (Carafate) 1 gm
PO QID
Requires acidic environment - avoid ANTACIDS and H2 Blockers
What medication used in treatment of PUD is also associated
with decreases in nosocomial PNA? .......Answer.........sucralfate
(Carafate) - mucosal protective agent