WGU D027 pre assessment Advanced Path
pharmacological Foundations (Latest
update 2026- 2027) Questions and
Answers 100% Correct {GRADE A}
A 45-year-old female fears that she is having a stroke and takes herself to an
emergency room. After several diagnostic and laboratory tests, the patient is
diagnosed with Cushing disease. Which lab abnormality would be present in this
patient?
A. Decreased adrenocorticotropic hormone (ACTH)
B. Increased adrenocorticotropic hormone (ACTH)
C. Increased cortisol
D. Decreased cortisol - correct answer C
A 26-year-old female presents to urgent care with complaints of extreme fatigue,
muscle aches, abdominal pain, numbness and tingling in her extremities, and
bloating. She explains that she has been experiencing gastrointestinal upset after
meals and has not had a bowel movement for the past four days. She denies having
any chronic diseases. The abdomen is distended and firm. Bowel sounds are present
in all four quadrants. The patient has a steady gait, though verbally complains of
feeling weak and off balance upon ambulation. Following antibody testing, Celiac
disease is suspected. Which follow-up tissue test, the gold standard for this suspected
diagnosis, should be ordered?
,WGU D027 pre assessment Advanced Path
pharmacological Foundations (Latest
update 2026- 2027) Questions and
Answers 100% Correct {GRADE A}
A. Endoscopy with stomach biopsy
B. Colonoscopy with large intestine biopsy
C. Endoscopy with small intestine biopsy
D. Colonoscopy with rectal biopsy - correct answer C
A 44-year-old woman has recently been diagnosed with advanced metastatic non-
small-cell lung cancer. Genetic testing is ordered to determine if the patient's tumor
has any genomic alterations and to guide treatment decisions. A few weeks later, the
patient's test results come back positive for a genetic mutation. The APN starts
osimertinib (Tagrisso). Based on this information, what types of genetic mutation
does this patient have? Choose 2 answers.
A. ALK mutation
B. EGFR mutation
C. BRCA mutation
D. MET amplification mutation - correct answer A, B
A 20-year-old male meets with an advanced professional nurse (APN) to discuss
symptoms that have been slowly progressing over the past several years. He is mainly
concerned because he has been falling frequently. Since childhood, his gait has
consisted of walking on his toes. During middle school, he was able to participate in
sports but was unable to participate in high school sports due to difficulty with
, WGU D027 pre assessment Advanced Path
pharmacological Foundations (Latest
update 2026- 2027) Questions and
Answers 100% Correct {GRADE A}
running and jumping. Lately, he has noticed it takes longer and is more difficult to
change positions from sitting to standing than it used to in the past. He has also been
waking up with muscle and joint stiffness. The APRN notes that his family history is
not significant for any chronic or genetic diseases. Which condition is likely to be the
cause of these symptoms?
A. Becker muscular dystrophy
B. Myotonic dystrophy
C. Facioscapulohumeral muscular dystrophy (FSHD)
D. Limb-girdle muscular dystrophy - correct answer A
A 16-year-old female presents to the clinic with complaints of coughing and
wheezing. The symptoms have been going on for several months, and she reports
that her coughing and wheezing becomes worse during soccer practice. Occasionally,
she wakes up at night and feels short of breath. She has a history of seasonal allergies
but has no personal or family history of respiratory diseases. Based on the patient's
presentation, which disease process is the patient likely exhibiting?
A. Bronchitis
B. Cystic fibrosis
C. Asthma
D. Sinusitis - correct answer C
pharmacological Foundations (Latest
update 2026- 2027) Questions and
Answers 100% Correct {GRADE A}
A 45-year-old female fears that she is having a stroke and takes herself to an
emergency room. After several diagnostic and laboratory tests, the patient is
diagnosed with Cushing disease. Which lab abnormality would be present in this
patient?
A. Decreased adrenocorticotropic hormone (ACTH)
B. Increased adrenocorticotropic hormone (ACTH)
C. Increased cortisol
D. Decreased cortisol - correct answer C
A 26-year-old female presents to urgent care with complaints of extreme fatigue,
muscle aches, abdominal pain, numbness and tingling in her extremities, and
bloating. She explains that she has been experiencing gastrointestinal upset after
meals and has not had a bowel movement for the past four days. She denies having
any chronic diseases. The abdomen is distended and firm. Bowel sounds are present
in all four quadrants. The patient has a steady gait, though verbally complains of
feeling weak and off balance upon ambulation. Following antibody testing, Celiac
disease is suspected. Which follow-up tissue test, the gold standard for this suspected
diagnosis, should be ordered?
,WGU D027 pre assessment Advanced Path
pharmacological Foundations (Latest
update 2026- 2027) Questions and
Answers 100% Correct {GRADE A}
A. Endoscopy with stomach biopsy
B. Colonoscopy with large intestine biopsy
C. Endoscopy with small intestine biopsy
D. Colonoscopy with rectal biopsy - correct answer C
A 44-year-old woman has recently been diagnosed with advanced metastatic non-
small-cell lung cancer. Genetic testing is ordered to determine if the patient's tumor
has any genomic alterations and to guide treatment decisions. A few weeks later, the
patient's test results come back positive for a genetic mutation. The APN starts
osimertinib (Tagrisso). Based on this information, what types of genetic mutation
does this patient have? Choose 2 answers.
A. ALK mutation
B. EGFR mutation
C. BRCA mutation
D. MET amplification mutation - correct answer A, B
A 20-year-old male meets with an advanced professional nurse (APN) to discuss
symptoms that have been slowly progressing over the past several years. He is mainly
concerned because he has been falling frequently. Since childhood, his gait has
consisted of walking on his toes. During middle school, he was able to participate in
sports but was unable to participate in high school sports due to difficulty with
, WGU D027 pre assessment Advanced Path
pharmacological Foundations (Latest
update 2026- 2027) Questions and
Answers 100% Correct {GRADE A}
running and jumping. Lately, he has noticed it takes longer and is more difficult to
change positions from sitting to standing than it used to in the past. He has also been
waking up with muscle and joint stiffness. The APRN notes that his family history is
not significant for any chronic or genetic diseases. Which condition is likely to be the
cause of these symptoms?
A. Becker muscular dystrophy
B. Myotonic dystrophy
C. Facioscapulohumeral muscular dystrophy (FSHD)
D. Limb-girdle muscular dystrophy - correct answer A
A 16-year-old female presents to the clinic with complaints of coughing and
wheezing. The symptoms have been going on for several months, and she reports
that her coughing and wheezing becomes worse during soccer practice. Occasionally,
she wakes up at night and feels short of breath. She has a history of seasonal allergies
but has no personal or family history of respiratory diseases. Based on the patient's
presentation, which disease process is the patient likely exhibiting?
A. Bronchitis
B. Cystic fibrosis
C. Asthma
D. Sinusitis - correct answer C
