Maryville University Of St. Louis

NURS 611 ADVANCED PATHOPHYSIOLOGY EXAM KEYPOINTS STUDIED AND REVISED FOR A GUARANTEE PASS Exam 1: Know Cell components and what they do: · Nucleus- Located in the center of the cell and contains the nucleolus which is composed of DNA, RNA, histones, and chromosomes. Primary functions are cell division, replication and repair of DNA, and transcription of RNA. · Ribosomes- Protein making factory (nucleoproteins). Goes into the nucleus, gets the “recipe”, transcribes the DNA, br...

NURS 611 ACIDOSIS AND ALKALOSIS CONDITIONS ADVANCED PATHOPHYSIOLOGY

Musculoskeletal Pathologies: Osteomyelitis Maryville University NURS 611: Advanced Pathophysiology Musculoskeletal Pathologies: Osteomyelitis Osteomyelitis is a bone infection affecting all ages, from neonates to adults (McCance & Huether, 2019). It is most common in males and ages between three and twelve years old adults (McCance & Huether, 2019). Factors that can predispose a patient to osteomyelitis development include various infections such as impetigo, cerebral abscesses...

QUESTIONS AND ANSWERS

Lithium labs - level, NA, Ca, P, EKG, Creatinine, Urinalysis, CBC, TSH bipolar meds: depression - lurasidone (13+), olanzapine + fluoxetine (10+)(symbyax) bipolar acute and mixed mania - aripiprazole, risperidone, olanzapine (13+), quetiapine (acute only), asenapine (10+) classic mood stabilizers - Lamotrigine (excellent medication to use), lithium, Depakote (avoid in females if possible due to PCOS and Pregnancy), Tegretol, Trileptal (no evidence for true Bipolar disorder) anti-depressa...

substance use disorder specifier criteria – Mild: 2-3 symptoms Moderate: 4-5 symtpoms Severe: >6 symptoms DSM for substance use disorder - over 12 months use increase amount persistant desire or can't cut down lots of time spent on substance craving failure to fill roles social/personal problems activities given up/reduced use when physically hazardous continue despite problem tolerence withdrawal abuse - use of any drug in a manner that deviates from approved social or med...

Bupropion (Wellbutrin) (NDRI) MOA 2D6 inHibitor (strong) 2B6 substrate Bupropion + 2B6 substrate -> hydroxy-bupropion + 2D6 -> inactive metabolite -stimulating antidepressent -enhances norepinephrine and dopamine -DOES NOT ENHANCE SEROTONIN -cognitive benefits -DOES NOT APPEAR TO EXACERBATE ANXIETY Bupropion (Wellbutrin) (NDRI) starting dose - XL 150mg AM preferred formulation d/t minimal seizure risk - SR 100mg BID separate by at least 8 hours - IR 75mg TID NOT RECOMMENDED D/T...

Patient comes in with symptoms of mania followed by periods of depression; what is it? - bipolar 1 patient comes in with hypomania/regular mood (euthymic) followed by periods of depression, what is it? - bipolar 2 how many symptoms of mania must you have to have "full" mania? - seven of thirteen what is the difference between mania and hypomania? - hypomania has less severe symptoms; 3 symptoms over shorter period of time (hypomania) Cyclothymia - a disorder that consists of mood swing...

Functions of the Endocrine System -Growth and development -Sex differentiation -Metabolism -Adaptation to an ever-changing environment -Regulation of digestion -Use and storage of nutrients (Electrolyte and water metabolism) -Reproductive functions The mechanism of hormones Hormones interact with high-affinity receptors. These are linked to one or more effector system in the cell. Some receptors are located on the surface of the cell. These act through second messenger mechanisms. O...

Phases of Grief · Shock and denial (days-weeks) acute anguish, lost patterns of conduct, resolution (months-year) · Denial, bargaining, depression, anger, acceptance · No real timeline, comes in waves Grief vs. MDD · Grief- Sx may meet syndromal criteria for MDD episode, but survivor rarely has morbid feelings of guilt, worthlessness, SI, or psychomotor retardation o Considers self bereaved o Dysphoria often triggered by thoughts or reminders of the deceased o Onset within 2 months...