Maryville University Of St. Louis

NURS 661 Exam 1 Full And Revised Latest Study Guide Grade A+. Nurse 661 Exam 1 Study Guide 1. Know signs and symptoms of dementia and diagnosis/treatment of new onset dementia S/S of Dementia: At least two of the following core mental functions must be significantly impaired to be considered dementia: Memory loss, Communication and language, Ability to focus and pay attention, reasoning and judgment, Visual perception. People with dementia may have problems with short-term memory, keeping ...

T/F Excitatory synapses cause hyperpolarization of post-synaptic cells. correct answer: False The resting potential of neurons is: correct answer: -60 mv (The answer is not on this list.) T/F The autonomic nervous system contains the sympathetic and the parasympathetic nervous system. correct answer: True In the motor end plate, the event that is the immediate trigger for exocytosis is: correct answer: Calcium Ions Draw an action potential in the axon of a neuron and indicate whi...

dopamine hypothesis correct answer: the theory that schizophrenia results from excessive activity of the neurotransmitter dopamine What is the path of dopamine suppression by 5-HT? correct answer: 5-HT2A antagonism by atypical antipsychotics decrease serotonin release, thereby stimulating downstream dopamine. Increased dopamine reduces glutamate which inhibits release of inhibitory GABA (inhibits dopamine) Mesolimbic dopamine hypothesis: Hyperactivity of dopamine neurons in the mesolimbi...

SSRIs correct answer: selective serotonin reuptake inhibitors Seriously Prepare Cities for the Flu Vaccine correct answer: -Sertaline (Zoloft) --Paroxetine (Paxil) -Citolpram(Celexa) -Escitalopram (Lexapro) -Fluoxetine HCl (Prozac) --Fluvoxamine (Luvox) -(Viibryd)Citol SSRI mechanism of action correct answer: Blocks the reuptake of serotonin (only serotonin) thus increasing it's effects All inhibit the serotonin transporter SERT SSRI side effects correct answer: Gastrointes...

Quetiapine (Seroquel) correct answer: Serotonin-Dopamine Antagonist Atypical antipsychotic How long does it take for quetiapine (Seroquel) to work correct answer: Psychotic and manic symptoms can improve within one week. It will take several week to have full effect on behavior. Recommended to wait 4-6 weeks to determine efficacy. May take 16-20 weeks to show good response on cognitive symptoms What does quetiapine do? correct answer: Decrease positive symptoms of schizophrenia What...

Which medication is contraindicated with liver impairment? correct answer: Atomoxine (Straterra) What is one of the birth defects associated with Litihum? correct answer: Ebstein's anomaly Which SSRI drug causes cardiovascular malformations in the first trimester of pregnancy? correct answer: Paroxetine (Paxil) Mechanism of action of a stimulant for ADHD Methylphenidate and amphetamine? correct answer: increases the intrasynaptic levels of both dopamine and norepinephrine What c...

The core symptoms of ADHD are linked to what area of the brain? correct answer: prefrontal cortex Selective attention is due to what area of the PFC malfunctioning? correct answer: dorsal ACC (anterior cingulate cortex) sustained attention and problem solving linked to what area of the brain? correct answer: DLPFC hyperactivity is linked to what area of the brain? correct answer: prefrontal motor cortex what test assessing sustained attention? correct answer: N-back test wher...

What is the medication that is the antidote for alprazolam? correct answer: flumazenil What is the MOA of pregabalin that makes it alleviate pain for people with fibromyalgia or chronic fatigue? correct answer: binds to the alpha 2 delta sub-units of voltage sensitive calcium channels What is an antagonist of caffeine correct answer: adenosine Diagnose this pt: Patient comes in with a CC of anxiety. She has been excessively worrying, increased arousal, increased tiredness and irritab...

Which medication has the SE of losing hair correct answer: Lithium The pt is bipolar, and had a partial response to depakote and now is going to be augmented with an atypical antipsychotic, the effects of atypical antipsychotics in non-psychotic mania may be due to what correct answer: indirect effect on glutamate release via 5H2A antagonism A pt has had some success with his current antidepression medication, has tried many different antidepressants, so you decide to augment with L-meth...

Fluoxetine (Prozac) Major Side Effects SSRI correct answer: -Sexual dysfunction (men: delayed ejaculation, erectile dysfunction; men and women: decreased sexual desire, anorgasmia) -Gastrointestinal (decreased appetite, nausea, diarrhea, constipation, dry mouth) -Mostly CNS (insomnia but also sedation, agitation, tremors, headache, dizziness) Note: patients with diagnosed or undiagnosed bipolar or psychotic disorders may be more vulnerable to CNS-activating actions of SSRIs -Autonomic (swea...