Pharmacology
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Drugs Acting on the Central Nervous System Definition, classification, pharmacological actions, dose, indications, and contraindications of General anaesthetics
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---7January 20262025/2026
- **General anaesthetics** are drugs that produce a reversible state of unconsciousness, analgesia, amnesia, and muscle relaxation, allowing painless surgical procedures. They act primarily on the central nervous system by enhancing inhibitory neurotransmission (mainly via GABA receptors) and/or inhibiting excitatory pathways. General anaesthetics may be administered by inhalation (e.g., volatile agents and gases) or intravenously. These agents depress cerebral activity, suppress reflex responses,...
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