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Immune reconstitution inflammatory syndrome: more answers, more questions
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---4augustus 20242024/2025A+
- Pathological basis of IRIS 
To understand the immunopathogenesis of IRIS it will be crucial to 
elucidate the intrinsic dynamics of immune cell recovery after 
initiation of HAART. The numerical increase in circulatory 
CD4+ T-cells has been well described, but much remains to be 
learned about the characteristics, specificity and function of these 
cells. Initial descriptions showed that activated memory cells 
(CD4+CD45RO+) account for the early incremental phase of 
CD4+ cell recovery followi...
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