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Iron overload in gestational alloimmune liver disease: still more questions than answers
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augustus 2024

2024/2025

A+
eover, terminal complement cascade activation, targeting a yet unidentified fetal liver epitope, has been demonstrated in the injured liver of affected babies.4 In our index family, the two previous pregnancies fulfilled the criteria of GALD (hypothesis that was confirmed a posteriori by specific histological examination). In the liver biopsy of the demised twin, we observed a very low degree of complement activation (MAC staining) contrasting with frank iron overload. We assumed that ...
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