Lecture HMS 4601
Substrate oxidation
Carbohydrates = saccharides
Mono-Saccharide Glucose, fructose, galactose
Quick spike in blood sugar.
Di-saccharides Maltose: Gluc + Gluc, Sucrose: Gluc + fruc, Lactose: Gluc + galact
Poly-saccharide starch, cellulose, glycogen.
Slow, Gradual rise in blood sugar
Glucose Glut-2 in the liver, Glut-4 muscle (contraction or insuline mediated)
Gets converted to glucose 6-phosphate glucose 1-phosphate glycogen).
In the liver glucose 6-phosphate can be transformed to glucose by glucose 6-phosphatase.
(NOT IN THE MUSCLE)
,2 types of stored glycogen (pools) in muscle
Primer: Glycogenin (as both the core and as the enzyme that stimulates self glycogensation)
Proglycogen (first phase of recovery, sensitive to CHO that you eat)
Macroglycogen (second phase of glycogenrecovery, more glucose per glycogencore, this is
the glycogen for supercompensation)
Fats
Triglycerides = glycerol + 3 fatty acids.
Adipose tissue = between 5-60% of body mass
Viseral WAT (white fat)
Subcuteanous WAT (white fat)
UPPER BODY VS LOWER BODY
Intramuscular fat = IMAT
Intermyofibrillar fat = IMF
Intramyocellular lipids = IMCL
Use when exercise
, Nomenclature
Skeletal muscle
Skeletal muscle
Substrate oxidation
Carbohydrates = saccharides
Mono-Saccharide Glucose, fructose, galactose
Quick spike in blood sugar.
Di-saccharides Maltose: Gluc + Gluc, Sucrose: Gluc + fruc, Lactose: Gluc + galact
Poly-saccharide starch, cellulose, glycogen.
Slow, Gradual rise in blood sugar
Glucose Glut-2 in the liver, Glut-4 muscle (contraction or insuline mediated)
Gets converted to glucose 6-phosphate glucose 1-phosphate glycogen).
In the liver glucose 6-phosphate can be transformed to glucose by glucose 6-phosphatase.
(NOT IN THE MUSCLE)
,2 types of stored glycogen (pools) in muscle
Primer: Glycogenin (as both the core and as the enzyme that stimulates self glycogensation)
Proglycogen (first phase of recovery, sensitive to CHO that you eat)
Macroglycogen (second phase of glycogenrecovery, more glucose per glycogencore, this is
the glycogen for supercompensation)
Fats
Triglycerides = glycerol + 3 fatty acids.
Adipose tissue = between 5-60% of body mass
Viseral WAT (white fat)
Subcuteanous WAT (white fat)
UPPER BODY VS LOWER BODY
Intramuscular fat = IMAT
Intermyofibrillar fat = IMF
Intramyocellular lipids = IMCL
Use when exercise
, Nomenclature
Skeletal muscle
Skeletal muscle
