Inhoudsopgave
Malaria..................................................................................................................................................... 5
Dengue .................................................................................................................................................... 7
Tuberculose ............................................................................................................................................. 7
Rickettsiose .............................................................................................................................................. 8
Q-koorts ................................................................................................................................................... 8
Leptospirose ............................................................................................................................................ 8
Humane herpes virussen ......................................................................................................................... 9
Salmonella typhi .................................................................................................................................... 10
Cholera .................................................................................................................................................. 10
Giardia lamblia....................................................................................................................................... 10
Campylobacter jejuni............................................................................................................................. 10
Acute gastro-enteritis ............................................................................................................................ 10
Cellulitis vs erysipilas ............................................................................................................................. 11
Overzicht huidziekten + plaatjes ........................................................................................................... 11
Allergie tegen medicatie ........................................................................................................................ 18
Huid begrippen bij psoriasis .................................................................................................................. 19
Antistoffen overzicht ............................................................................................................................. 22
Ziekte van Kawasaki ............................................................................................................................... 23
Ziekte van henoch schonlein ................................................................................................................. 23
Hand-voet-mondziekte .......................................................................................................................... 24
Sclerodermie ......................................................................................................................................... 24
Dermatomyositis ................................................................................................................................... 24
Endocarditis ........................................................................................................................................... 24
HIV ......................................................................................................................................................... 25
Toxoplasmose ........................................................................................................................................ 26
Meningitis .............................................................................................................................................. 27
Sepsis ..................................................................................................................................................... 28
Hepatitis ................................................................................................................................................ 29
Epstein barr virus ................................................................................................................................... 29
Opportunistische infecties..................................................................................................................... 30
Antibiotica overzicht .............................................................................................................................. 31
Therapeutische breedte ........................................................................................................................ 32
Minimaal inhibitoire concentratie ......................................................................................................... 33
Resistentie ............................................................................................................................................. 33
,Fasen bacteriële groei ........................................................................................................................... 34
Verwekkers pneumonie ......................................................................................................................... 34
Verwekkers UWI .................................................................................................................................... 35
Overzicht bacteriën ............................................................................................................................... 36
Verticale transmissie.............................................................................................................................. 37
Coagulase + katalase test ...................................................................................................................... 37
Virulentiefactoren.................................................................................................................................. 38
PCR......................................................................................................................................................... 39
Allergologisch onderzoek ...................................................................................................................... 39
Bacteriën zichtbaar maken .................................................................................................................... 39
SCID ....................................................................................................................................................... 40
CVID ....................................................................................................................................................... 40
IgG 1deficiëntie...................................................................................................................................... 40
Chronische granulomateuze ziekte ....................................................................................................... 40
Type 1-type 4 reacties ........................................................................................................................... 41
Influenza vaccin effectiviteit .................................................................................................................. 41
Definities mmi ....................................................................................................................................... 42
,Vlekjesziekten
Ziekte Kenmerken
1 Mazelen: - CCCK: cough, coryza, conjunctivitis en koplikse
rubeola vlekjes (vlekjes na 1-3 dagen, verheven in het
wangslijmvlies)
- Ook: koorts, algehele malaise, faryngitis
- Na 3-7 dagen grofvlekkig exantheem op het hele
lichaam (beginnen in gezicht en nek)
- Complicaties:
- encefalitis, subacute scleroserende
panencefalitis en secundaire bacteriële infecties
Diagnostiek = antistoftiter dag 14 (virus is al verdwenen)
- Zeer besmettelijk
- Alleen infectieus voor de mens
- Enkelstrengs RNAvirus
2 Roodvonk: 1. Acuut begin met koorts, braken, angina
scarlattina (keelontsteking) met wit wegveegbaar beslag.
(GAS: strep. Tachycardie, lymfadenopathie hals en
Pyogenes) suboccipitaal
2. Dag 2: exantheem over het gelaat met
uitsparing rond de mond. Puntvormig,
confluerend en wegdrukbaar, ook
frambozentong
3. Week 2: Vervelling handen en voeten
Behandeling = penicilline
3 Rubella: Rode - Malaise, conjunctivitis, hoofdpijn, subfebriele
hond temperatuur
- Besmettelijk 5 dagen voor exantheem en 5
dagen na exantheem dmv druppelinfectie
- Eerste 16 weken zwangerschap: aangeboren
afwijkingen.
4 X
5 Erythema - Typisch schoolgaand kind
infectiosum - Bij kinderen mild: Exantheem, slapped cheecks,
(parvo B19) maculopapulaire rash over het gehele lichaam.
Daarna verhoging en milde griepachtige
verschijnselen.
- Bij volwassenen: symmetrische
gewrichtsklachten
- Complicatie verticale transmissie = hydrops
foetalis
, 6 Exanthema - Meest voorkomend exantheem bij jonge
subitum: kinderen
roseola (HHV6) - Acuut begint met hoge koorts die na 3 dagen
daalt, daarna kleinvlekkig roze exantheem
7 Bof - Koorts, algehele malaise en spierpijn, daarna
(Paramyxovirus) parotitis oorspeekselklieren
- Complicatie = orchitis, encefalitis, pancreatitis
8 Waterpokken - Complicaties: Encefalitis, cerebellaire ataxie,
(VZV) hemorrhagische varicella
Behandeling = jeukbestrijding
Behandeling risicogroep = aciclovir
Complicaties : encefalitis, meningitis, cerebellarie
ataaxie, bacteriële superinfectie, post-herpetische
neuralgie
9 Borreliose Vroeg gelokaliseerd
(Borellia - EM, malaise, koorts, hoofdpijn
burgdorferi) Vroeg gedissemineerd
- Vroege neuorborreliose, lyme-artritis,
myocarditis met AV-blokkade
Laat gedissemineerd
- Acrodermatitis chronica atroficans,
neuroborreliose, lyme-artritis, gedilateerde
cardiomyopathie
Malaria..................................................................................................................................................... 5
Dengue .................................................................................................................................................... 7
Tuberculose ............................................................................................................................................. 7
Rickettsiose .............................................................................................................................................. 8
Q-koorts ................................................................................................................................................... 8
Leptospirose ............................................................................................................................................ 8
Humane herpes virussen ......................................................................................................................... 9
Salmonella typhi .................................................................................................................................... 10
Cholera .................................................................................................................................................. 10
Giardia lamblia....................................................................................................................................... 10
Campylobacter jejuni............................................................................................................................. 10
Acute gastro-enteritis ............................................................................................................................ 10
Cellulitis vs erysipilas ............................................................................................................................. 11
Overzicht huidziekten + plaatjes ........................................................................................................... 11
Allergie tegen medicatie ........................................................................................................................ 18
Huid begrippen bij psoriasis .................................................................................................................. 19
Antistoffen overzicht ............................................................................................................................. 22
Ziekte van Kawasaki ............................................................................................................................... 23
Ziekte van henoch schonlein ................................................................................................................. 23
Hand-voet-mondziekte .......................................................................................................................... 24
Sclerodermie ......................................................................................................................................... 24
Dermatomyositis ................................................................................................................................... 24
Endocarditis ........................................................................................................................................... 24
HIV ......................................................................................................................................................... 25
Toxoplasmose ........................................................................................................................................ 26
Meningitis .............................................................................................................................................. 27
Sepsis ..................................................................................................................................................... 28
Hepatitis ................................................................................................................................................ 29
Epstein barr virus ................................................................................................................................... 29
Opportunistische infecties..................................................................................................................... 30
Antibiotica overzicht .............................................................................................................................. 31
Therapeutische breedte ........................................................................................................................ 32
Minimaal inhibitoire concentratie ......................................................................................................... 33
Resistentie ............................................................................................................................................. 33
,Fasen bacteriële groei ........................................................................................................................... 34
Verwekkers pneumonie ......................................................................................................................... 34
Verwekkers UWI .................................................................................................................................... 35
Overzicht bacteriën ............................................................................................................................... 36
Verticale transmissie.............................................................................................................................. 37
Coagulase + katalase test ...................................................................................................................... 37
Virulentiefactoren.................................................................................................................................. 38
PCR......................................................................................................................................................... 39
Allergologisch onderzoek ...................................................................................................................... 39
Bacteriën zichtbaar maken .................................................................................................................... 39
SCID ....................................................................................................................................................... 40
CVID ....................................................................................................................................................... 40
IgG 1deficiëntie...................................................................................................................................... 40
Chronische granulomateuze ziekte ....................................................................................................... 40
Type 1-type 4 reacties ........................................................................................................................... 41
Influenza vaccin effectiviteit .................................................................................................................. 41
Definities mmi ....................................................................................................................................... 42
,Vlekjesziekten
Ziekte Kenmerken
1 Mazelen: - CCCK: cough, coryza, conjunctivitis en koplikse
rubeola vlekjes (vlekjes na 1-3 dagen, verheven in het
wangslijmvlies)
- Ook: koorts, algehele malaise, faryngitis
- Na 3-7 dagen grofvlekkig exantheem op het hele
lichaam (beginnen in gezicht en nek)
- Complicaties:
- encefalitis, subacute scleroserende
panencefalitis en secundaire bacteriële infecties
Diagnostiek = antistoftiter dag 14 (virus is al verdwenen)
- Zeer besmettelijk
- Alleen infectieus voor de mens
- Enkelstrengs RNAvirus
2 Roodvonk: 1. Acuut begin met koorts, braken, angina
scarlattina (keelontsteking) met wit wegveegbaar beslag.
(GAS: strep. Tachycardie, lymfadenopathie hals en
Pyogenes) suboccipitaal
2. Dag 2: exantheem over het gelaat met
uitsparing rond de mond. Puntvormig,
confluerend en wegdrukbaar, ook
frambozentong
3. Week 2: Vervelling handen en voeten
Behandeling = penicilline
3 Rubella: Rode - Malaise, conjunctivitis, hoofdpijn, subfebriele
hond temperatuur
- Besmettelijk 5 dagen voor exantheem en 5
dagen na exantheem dmv druppelinfectie
- Eerste 16 weken zwangerschap: aangeboren
afwijkingen.
4 X
5 Erythema - Typisch schoolgaand kind
infectiosum - Bij kinderen mild: Exantheem, slapped cheecks,
(parvo B19) maculopapulaire rash over het gehele lichaam.
Daarna verhoging en milde griepachtige
verschijnselen.
- Bij volwassenen: symmetrische
gewrichtsklachten
- Complicatie verticale transmissie = hydrops
foetalis
, 6 Exanthema - Meest voorkomend exantheem bij jonge
subitum: kinderen
roseola (HHV6) - Acuut begint met hoge koorts die na 3 dagen
daalt, daarna kleinvlekkig roze exantheem
7 Bof - Koorts, algehele malaise en spierpijn, daarna
(Paramyxovirus) parotitis oorspeekselklieren
- Complicatie = orchitis, encefalitis, pancreatitis
8 Waterpokken - Complicaties: Encefalitis, cerebellaire ataxie,
(VZV) hemorrhagische varicella
Behandeling = jeukbestrijding
Behandeling risicogroep = aciclovir
Complicaties : encefalitis, meningitis, cerebellarie
ataaxie, bacteriële superinfectie, post-herpetische
neuralgie
9 Borreliose Vroeg gelokaliseerd
(Borellia - EM, malaise, koorts, hoofdpijn
burgdorferi) Vroeg gedissemineerd
- Vroege neuorborreliose, lyme-artritis,
myocarditis met AV-blokkade
Laat gedissemineerd
- Acrodermatitis chronica atroficans,
neuroborreliose, lyme-artritis, gedilateerde
cardiomyopathie
