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This provides a comprehensive overview of cholesterol metabolism, detailing its sources, synthesis, structure, and functions. Cholesterol is obtained from dietary intake and endogenous synthesis, occurring mainly in the liver and all body cells. Synthesis is stimulated by increased Acetyl-CoA, a process influenced by insulin. The pathway involves several steps, notably the conversion of HMG-CoA to Mevalonate by HMG-CoA reductase, which is the slowest and most regulated step, inhibited by statins...

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