hesi patho

HESI Pathophysiology Review 1. What is TPA? What are at least 2 conditions where you might see it given as a medication? Why would we not give it? tPA: clot busting agent used to reduce the effects of CVA (stroke) in some individuals. It is contraindicated for anticoagulant drugs. The release of tissue plasminogen (tPA) from injured blood vessels and tissues, converts plasminogen to plasmin. Plasmin is a potent enzyme that digests fibrin strands (this leads to clot dissolution). 2. Know ...

HESI Pathophysiology Review 1. What is TPA? What are at least 2 conditions where you might see it given as a medication? Why would we not give it? tPA: clot busting agent used to reduce the effects of CVA (stroke) in some individuals. It is contraindicated for anticoagulant drugs. The release of tissue plasminogen (tPA) from injured blood vessels and tissues, converts plasminogen to plasmin. Plasmin is a potent enzyme that digests fibrin strands (this leads to clot dissolution). 2. Know ...

What cholesterol is the good cholesterol? (Hint - remember LDL = lousy) HDL: the "good" lipoprotein; has a low lipid content and is used to transport cholesterol AWAY from the peripheral cells to the liver, where it undergoes catabolism and excretion; is increased with exercise; protects women until after menopause; smoking decreases HDL levels; 11. What kind of immunity do we get from vaccines? How about from mother to baby? How do you get active immunity? Vaccines: Acquired, Active, A...

2. Know the triad that would lead you to conclude your patient is experiencing cardiac tamponade Fluid compresses the heart, prevents stretching & filling, reduces CO Arterial pressure falls, venous pressures rise, pulse pressure narrows Beck’s Triad: Distant, muffled heart sounds (like under water, fluid), JVD, decreased BP =EMERGENCY pericardiocentesis with surgical repair as appropriate is needed (16-18 gauge needle inserted into pericardial space to relieve pressure and analyze fl...