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NUR 2063 Pathophysiology Exam 1 Study Guide 2021/2022
Module 1 
1. What happens during the alarm phase of Hans Selye’s General Adaptation 
Syndrome? 
 à “Fight or flight” response 
 Hypothalamus senses need to activate the GAS in response to a stimulus 
(stressor) putting the balance of homeostasis at risk 
 Hypothalamus then secretes corticotropin-releasing hormone (CRH) to 
activate SNS which also stimulates adrenal medulla to release 
catecholamines-norepinephrine & epinephrine 
 During the phase, there is reduced resistance t...
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