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The Role of Measurable Residual Disease (MRD) at Time of Allogeneic Hematopoietic Cell Transplantation in Adults with Acute Lymphoblastic Leukemia Transplanted after Myeloablative Conditioning. A Study on Behalf of the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation Jiri Pavlu MD1 , Myriam Labopin MD2 , Riitta Niittyvuopio MD3 , Gerard Soci
e MD, PhD4 , Ibrahim Yakoub-Agha MD, PhD5 , Depei Wu MD6 , Peter Remenyi MD7 , Jakob Passweg MD, MS8...

Introduction HCV, the deadly virus has infected almost 3% of the world population. Most of the infected patients develop chronic infection leading to end stage hepatocellular carcinoma. A better understanding of mechanism of infection and the potential host co-factors facilitating its replication is an urgent need of the hour for the release of disease burden and vaccine development [1-3]. In multicellular organisms, movement of ions, proteins and water is controlled by barriers ...

Introduction Resource monitoring has long been recognized as a cornerstone of biodiversity and conservation science [1,2,3]. In 2010, at the 10th Conference of the Parties of the Convention on Biological Diversity (CBD), 193 nations agreed to twenty ‘‘Aichi Biodiversity Targets’’, and in doing so committed to updating their National Biodiversity Strategies and Action Plans and developing monitoring programs to assess progress [4]. The Aichi Targets rely upon indicators to ...

INTRODUCTION Medicinal plants are in use for the purpose of treatment of different ailments since centuries. There has been an immense increase in sales of herbal OTC (Over the counter drugs. This is growing to a billion dollar industry. The need for safety and efficacy has also escalated since the western interest has grown. Thus the need for standardization has come into view. The process of evaluation of the quality and purity of crude drugs by means of various parameters like morphological,...

Abstract: Folklore is an important repository of traditional knowledge for most of the communities of North East India. Before the arrival of western education in the region, most of the tribes followed an Oral tradition, and hence, folklore assumed significant importance as an alternate source of literature. Due to the absence of a written script, mediums such as songs, legends, myths, graphic patterns and designs, and artifacts became the transmitters of their tribe’s ancient history ...

6. The daily closing values of the Dow Jones Industrial Average over a period of 30 days are best described as _____ data. a. cross-sectional b. discrete c. time-series d. nominal 7. A variable is classified as ordinal if a. there is a natural ordering of categories. b. the data is randomly selected. c. the data arise from continuous measurements. d. we track the variable through a period of time. 8. Categorizing a numeric age variable as "young," "middle-aged,"...

I INTRODUCTION Genetics is the scientific study of inherited variation. Human genetics is the scientific study of inherited human variation. This field has been energized in recent years by the Human Genome Project. Scientists expect that the project will lead to the development of new drugs targeted to specific genetic disorders. Increasingly, modern genetics involves genetic engineering; a technique used to manipulate genes and has produced many advances in medicine. II PRINCIPLES OF GENET...

Background and Aim: Rheumatoid arthritis (RA), an autoimmune disease, is known as the most prevalent type of polyarticular inflammatory arthritis with a variety of features, including continual synovial inflammation, bony erosions, and progressive destruction with varying physical disability and degrees of pains. The aim of this study is to provide the knowledge about plants used in rheumatoid arthritis treatment by people residing in Gusau, Zamfara State, Nigeria. Materials and Methods: The ...

The liver is the central organ in the metabolism and detoxification of drugs and toxins. Consequently, drugs affect the liver more frequently than any other organ and place the liver at great risk for toxic damage (Bussieres and Habra, 1995). After absorption by the intestines, drugs reach the liver via the portal system. In the hepatocytes, these chemicals undergo complex metabolic processes to be converted into hydrophilic substances, readily soluble in the blood stream and easily eliminated t...

INTRODUCTION The liver is a major target for the chemical induced toxicity, as it participates in the metabolism, detoxification, and secretory functions. Liver disease is a worldwide problem and in most of the cases, liver damage is due to oxidative stress. Liver damage if not managed at the right time, may progress from steatosis to chronic hepatitis, fibrosis, cirrhosis and even hepatocellular carcinoma [1]. The progressive and chronic liver assault triggers the progressive wound healing r...