Group Drugs Mechanism Side-Effects Sub-types Taken Diseases
β₂ Adrenergic Allouterol β₂ receptor → Gs Tremors, Palpitations, SABA - Short acting Inhalation, Oral, Asthama(acute),
receptors Terbutaline protein → Adenylyl Tachycardia, LABA – Lipophilic IV (emergency) COPD
Metaproternol cyclase enzyme → ATP ↓ Serum K⁺ level Stays in membrane
Pirobuterol → cAMP (↑) → Relax Arrhythmias, longer, long active
Salbutanol(SABA) smooth muscle Hypokalemia
Salmeterol(LABA)
Formeterol(LABA)
Indaceterol(ULABA)
β₁ Adrenergic Epinephrine Stimulate both β₁ Arrhythmia, Oral CVD
receptors Isoproterenol (heart) and β₂ (lungs) ↑ Heart rate,
receptors ↑ Force of contraction
Muscarinic Ipratropium(SAMA) → Block M3 receptor → Dry mouth(Less Side- SABA Oral Inhalation Asthama, Best for
Receptor Tiotropium(LAMA) ↓ Vagal tone → Effects) LABA COPD
Relaxation /
Bronchodilation
Methylxanthines Theophylline → Block Nausea, Arrhythmia, Oral COPD
Theobromine phosphodiesterase Seizures
enzyme → CAMP does
not break down
↑ CAMP because
phosphodiesterase
cannot convert CAMP
→ AMP, Block
Xanthiene
Leukotriene Ziluetim(leukotriene → Block leukotriene Headacche, GI upset, Oral Chronic Asthama
Antagonists synthesis lnhibitor) receptors → liner toxic
Zafirlukast ↓ Inflammation →
Montelukst ↓ Bronchoconstriction
β₂ Adrenergic Allouterol β₂ receptor → Gs Tremors, Palpitations, SABA - Short acting Inhalation, Oral, Asthama(acute),
receptors Terbutaline protein → Adenylyl Tachycardia, LABA – Lipophilic IV (emergency) COPD
Metaproternol cyclase enzyme → ATP ↓ Serum K⁺ level Stays in membrane
Pirobuterol → cAMP (↑) → Relax Arrhythmias, longer, long active
Salbutanol(SABA) smooth muscle Hypokalemia
Salmeterol(LABA)
Formeterol(LABA)
Indaceterol(ULABA)
β₁ Adrenergic Epinephrine Stimulate both β₁ Arrhythmia, Oral CVD
receptors Isoproterenol (heart) and β₂ (lungs) ↑ Heart rate,
receptors ↑ Force of contraction
Muscarinic Ipratropium(SAMA) → Block M3 receptor → Dry mouth(Less Side- SABA Oral Inhalation Asthama, Best for
Receptor Tiotropium(LAMA) ↓ Vagal tone → Effects) LABA COPD
Relaxation /
Bronchodilation
Methylxanthines Theophylline → Block Nausea, Arrhythmia, Oral COPD
Theobromine phosphodiesterase Seizures
enzyme → CAMP does
not break down
↑ CAMP because
phosphodiesterase
cannot convert CAMP
→ AMP, Block
Xanthiene
Leukotriene Ziluetim(leukotriene → Block leukotriene Headacche, GI upset, Oral Chronic Asthama
Antagonists synthesis lnhibitor) receptors → liner toxic
Zafirlukast ↓ Inflammation →
Montelukst ↓ Bronchoconstriction
