LEHNE’S PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE

This comprehensive test bank covers all units of Lehne’s Pharmacotherapeutics for Advanced Practice Nurses and Physician Assistants, 2nd Edition by Laura D. Rosenthal and Jacqueline Rosenjack Burchum. Updated for 2026/2027, it includes multiple-choice, true/false, and case-based questions designed to reinforce pharmacology concepts, clinical applications, and safe drug administration practices for advanced practice nursing and physician assistant students. Chapter/Unit Coverage: Unit 01:...

After prescribing transdermal estrogen spray, which of the following patient statements suggests they understand how to apply the medication to achieve the desired effect? A. "I will apply the medication to my waistline and shoulders." B. "My abdomen and arms are the primary point of application." C. "This medication will work best if applied to my breasts and abdomen." D. "I need to put the medication on my thighs and calves." D. "I need to put the medicati...

Ch 59 Drug Therapy of Rheumatoid Arthritis 598. A patient will begin taking hydroxychloroquine [Plaquenil] for rheumatoid arthritis. The patient is currently taking high-dose NSAIDs and methotrexate. What will the nurse teach the patient? a. That an eye examination is necessary at the beginning of therapy with this drug Ch 59 Drug Therapy of Rheumatoid Arthritis 599. A patient will begin taking etanercept [Enbrel] for severe rheumatoid arthritis. The patient has been taking methotrexate [Rheum...

Muscle paralysis for 5 to 10 minutes A patient receives succinylcholine (Anectine) before endotracheal intubation. What would the nurse expect? Administer lorazepam (Ativan) intravenously The physician orders a intravenous infusion of cisatracurium (Nimbex) for a patient receiving mechanical ventilation. It is most important for the nurse to take which action before starting the infusion? Major burns during the emergent phase Succinylcholine [Anectine] is contraindicated in a patient with w...

An APRN works in a urology clinic under the supervision of a physician who does not restrict the types of medications the APRN is allowed to prescribe. State law does not require the APRN to practice under physician supervision. How would the APRN's prescriptive authority be described? A. Full authority B. Independent C. Without limitation D. Limited authority ANS: B The APRN has independent prescriptive authority because the regulating body does not require that the APRN work under p...

Define pharmacodynamics? The study of what drugs do to the body and how they do it. The study of the biochemical and physiologic effects of drugs and the molecular mechanisms by which those effects are produced Define dose-response relationship? The relationship between the size of an administered dose and the intensity of the response produced. For most drugs, the dose-response relationship is ________. That is, the response gets more ________ with ________ dosage. -graded -intense -i...

Two major forms of heart failure 1) heart failure with left ventricular systolic dysfunction 2) diastolic heart failure, also known as heart failure with preserved LV ejection fraction Progressive, often fatal disorder characterized by ventricular dysfunction, reduced cardiac output, insufficient tissue perfusion, and signs of fluid retention Heart failure Drugs recommended for treatment of heart failure diuretics, inhibitors of RAAS, beta blockers, and digoxin Heart failure is a syndrome...

Define idiosyncratic effect An uncommon drug response resulting from a genetic predisposition. *Ex:) when people with glucose-6-phosphate dehydrogenase (G6PD) deficiency take drugs such as sulfonamides or aspirin, they develop varying degrees of red blood cell hemolysis, which may become life threatening. What is the intensity of an allergic drug reaction based on? What is it not based on? - the degree of immune system sensitization - it is not based on drug dosage. What is the risk...

Define adverse drug reaction Any noxious, unintended, and undesired effect that occurs at normal drug doses Define allergic reaction An immune response triggered by re-exposure of a previous immune system sensitizing drug. Define carcinogenic effect The ability of certain medications and environmental chemicals to cause cancers. Define hepatotoxic drugs Drugs that, after metabolism in the liver, are converted to toxic products that can injure liver cells. Define iatrogenic disease. A di...

It selectively activates alpha2 receptors in the central nervous system (CNS) The nurse is preparing to administer a dose of clonidine [Catapres]. Which is the best description of the action of this drug? Drowsiness and dry mouth The nurse is assessing a patient in a clinic who has been taking clonidine [Catapres] for hypertension. Which clinical findings are most indicative of an adverse effect of this drug? "If you stop taking this drug abruptly, your blood pressure might go up very hig...