BIOC20

BIOC20 LEC 10 RETROVIRUSES & HIV EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS LATEST UPDATE GRADED A++ HIV replicates in and kills.... lymphocytes and macrophages - both cells are CD4+, glycoprotein found on immune cell surface) Cd4+ is a.... Cd4+ is a glycoprotein found in immune cell surfaces Infection results in •Infection results in depletion of CD4+ T cells, rendering the host immunocompromised Phases of HIV infection 1) Acute Infection 2) Clinical latency 3) AIDS Expl...

BIOC20 - LECTURE 3 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED capsids with helical symmetry - organized as helical tubes composed of identical, repeating subunits - longer the genome, the longer the helical nucleocapsid parameters that define symmetry of helical capsids - # of subunits per turn (µ) - displacement along the helical axis btw one capsid subunit and the next (p) - pitch (P) is the distance along the axis corresponding to one turn P = µ *p virus envelope...

BIOC20 LEC 1 + 2 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED LATEST UPDATE Viruses are obligate intracellular parasites. What does this mean? They need to get inside the cell in order to replicate. This is because they must hijack the host cell metabolic machinery because they do not possess their own Viruses go from cell to cell or host to host? Both T/F Viruses can spread across species barriers True This is called the zoonotic spread Which forms of life can viruses ...

BIOC20 LEC 6 - CORONAVIRUS EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED LATEST UPDATE Briefly describe the Coronavirus Spherical envelop particles crowned with trimetric spikes What diseases can Coronavirus cause - Mostly cause respiratory illnesses in humans - Rare cases can cause gastroenteritis and encephalitis - Also vet diseases such as feline peritonitis, infectious bronchitis, murine hepatitis SARS coronavirus transmission and origin - Transmitted by direct contac...

BIOC20 PRACTICE QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS LATEST UPDATE GRADED A++ Which of the following would not be a nucleic acid found in a viral genome? a. an RNA:DNA hybrid b. dsDNA c. ssDNA d. ssRNA e. dsRNA a. an RNA:DNA hybrid Assume that you are a scientist in the 1800s and do not have access to modern technology. If you wanted to show that an infectious agent is a virus, what experiment could you do? a. Show that the agent can be seen under a light microscope b. ...

BIOC20 LECTURE 7 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED What type of viruses are picorna, flavi and toga viruses? +ssRNA. What is the structure of picornaviruses? Small, naked (non-enveloped) capsid, linear genome. How do picornaviruses bind to cellular receptors? Depressions or loop regions on the surface. How many copies of VP do mature virions contain? 60. Instead of the 5' cap, what do picornaviruses have? They have VPg attached covalently to the 5' end...

LECTURE 1 AND 2 BIOC20 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++ What does a nucleotide consist of? Base, phosphate, and sugar templated polymerization Replication of a strand using a template strand. Add nucleotides one by one. Enzyme that makes RNA transcript RNA polymerase 2 Differences between DNA and RNA Sugar= ribose and deoxyribose Uracil and thymine ribonucleotides and deoxyribonucleotides Use cake analogy for Replication and Protein synthesis Recipe boo...

BIOC20 LECTURE 8 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS LATEST UPDATE Filoviridae Family of filamentous, enveloped RNA viruses. Negative sense ssRNA Single-stranded RNA with reverse transcription. Marburg virus First identified in 1967, causes severe disease. Ebolavirus Emerging virus causing hemorrhagic fever. Zaire ebolavirus (ZEBOV) Most fatal ebolavirus species known. Sudan ebolavirus (SEBOV) Ebolavirus species with no vaccine available. Cote d'Ivoire ebolavirus...

BIOC20 LECTURE 5 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED LATEST UPDATE Membrane Fusion Process where viral and host membranes merge. Hemifusion Initial stage of membrane fusion without full merging. Influenza Virus HA Hemagglutinin protein mediating membrane fusion. Fusion Peptides Peptides that facilitate membrane fusion in viruses. Class I Fusion Proteins α-helical proteins forming trimers for fusion. Class II Fusion Proteins β-sheet proteins forming dimers ...

BIOC20 LECTURE 6 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED How much of the genome does gene 1 occupy in CoV? What does it translate into? 2/3, precursor polyproteins. What does the other 1/3 of the genome consist of? Structural, non-structural and packaging proteins. Name the proteins of CoV. HE: hemagglutinin estrase. S: Spike E: small envelope protein. M: membrane protein. N: nucleocapsid protein. What is the structure of CoV? Enveloped with helical nucleocapsid...