PED1003

PED1003 FORMATIVE QUIZ EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++ What is a barrier to glomerular filtration but not active tubular secretion? Plasma protein binding When the drug is in the stomach acid, it will pass through the stomach walls best if it is Unionised The equilibrium dissociation constant (Kd) is a measure of a drugs Affinity Drugs that are high plasma protein bound have what type of volume of distribution? Low Agonism at which receptors results in ...

PED1003 PHARMACOLOGY EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++ LATEST UPDATE Pharmacology The study of drugs and their interactions with living systems Pharmacodynamics The effects of a drug on the body Study of this allows us to determine appropriate dose range for patients and compare the effectiveness and safety of one drug to another Pharmacokinetics What the body does to the drug (absorption, distribution, metabolism, excretion) Study allows us to design an...

PED1003 - ADME EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++ LATEST UPDATE What are the 2 types of drug movement? Bulk flow - 99% bound to plasma proteins in the blood (chemical nature as no effect) Diffusion across barriers - GI, BBB (chemical nature has big effect) What is drug absorption? The transfer of exogenous compound from the site of administration into the systemic circulation (plasma)? What are the 6 routes of drug administration? Oral/rectal, intravenous, per...

REVIEWED: PED1003 L16 DRUGS OF ABUSE (TBC: 20:03) EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++ What is drug abuse? Use of drugs for non-therapeutic purposes What are drugs of abuse? Drugs that have the potential to be used for non-therapeutic purposes (i.e., recreationally) What do all drugs of abuse have in common? How do they differ? Different chemical classes that act on different molecular targets BUT (directly or indirectly) all trigger increase in dopamine rele...

PHARMACOLOGY - PED1003 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++ What is pharmacodynamics Effect of drugs on the body What is pharmacokinetics what the body does to the drug What are the 2 different classes of drugs . Naturally occurring . Synthetic What does pharmacodynamics allow us to determine in terms of patients (3) . Appropriate dosage range . Compare efficacy . Compare safety What does the acronym ADME stand for in terms of pharmacokinetics . Absorption...