PED1003

PED1003 PHARMACOLOGY LECTURE 4 - 6 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++ When is an IV used to administer a drug? (3 reasons) - when a rapid onset of action is needed - when high dose control is required - when a drug is poorly absorbed or metabolised in GI tract What are the 3 types of drug injections available? Intravenous Intramuscular Subcutaneous first pass metabolism the substance degradation of an orally administered drug caused by enzyme metabolism in ...

PED1003 24 ANTIPROTOZOALS EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++ What are protozoal infections? parasitic diseases caused by organisms formerly classified in the kingdom Protozoa. What are Leishmania, Acanthamoeba and malaria? Protozoal infections What is malaria? Malaria is a life-threatening disease caused by parasites that are transmitted to people through the bites of infected mosquitos How much of the world population is at risk of malaria? Half What percen...

PED1003 PHARMACOLOGY LECTURE 17-18 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++ LATEST UPDATE What are the 3 main sex hormones? Oestrogen Testosterone Progesterone What do hormones control and regulate? Reproduction Metabolism Growth/development Body Temperature Body defences Warer levels There are over ____ different types of hormones at work in our bodies at a given time 50 What is homeostasis? Maintaining a stable internal environment What are the examples o...

NEUROTRANSMISSION PED1003 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++ What is the nervous system? Complex network of interconnecting neurones What is a neurone? Excitable cells which release neurotransmitters What is neuronal signalling? Transfer of information along or between neurones What are the two types of neuronal signalling? Chemical, Electrical What is electrical signalling? Cell body communicates with axon using its electrical impulses (Action potentials)....

PED1003 13 ASTHMA EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++ LATEST UPDATE What does parasympathetic innervation control? Bronchial and vascular smooth muscle amd glands What neurotransmitter is used during parasympathetic innervation? Acetylcholine What receptor does the acetylcholine bind to in parasympathetic innervation? M3 cholinergic receptors What does the binding of ACh to M3 receptors trigger an increase in? IP3 What is the result of parasympathetic innerva...

PED1003 PHARMACOLOGY LECTURE 21 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++ What is inflammation? The local accumulation of fluid containing plasma proteins and WBCs Is inflammation specific or non-specific? non-specific Is inflammation an immediate response? Yes What is the aims of inflammation? - Restrict damage or infection to localised area - Remove causative agent and damaged tissue - Promote immune cell access to site Is inflammation in the 1st, 2nd or 3rd li...

PED1003 PHARMACOLOGY LECTURE 23 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++ What is selective toxicity? ability of drug to kill or inhibit pathogen while damaging host as little as possible What do invading cells include? Bacteria, fungi, viruses and parasites Why has there been a drop in the number of new antibiotics reaching market in the past 10 years? - Too little profit - government restrictions - lack of new biological targets etc Who coined the term "magic...

PED1003 PHARMACOLOGY LECTURE 14 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++ LATEST UPDATE Parkinson's disease is idiopathic, what does this mean? The cause of the disease is unknown What is Parkinsonism? Disease with Parkinson-like symptoms without actually having the disease and with the cause known What causes parkinsonism? Any condition (that isn't Parkinson's disease) with loss of DA transmission What are the examples of what can cause parkinsonism? Drugs...

PED1003 8 TOXICOLOGY EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++ what is toxicology noxious effects of chemicals on living systems xenobiotics foreign chemicals the organism doesn't produce simplest way to measure its toxicity is its LD50 what is an LD50 lethal dose for 50% of the population ( in lab) in acute toxicity, symptoms develop _______ whilst chemical is ____ __ ____ and are _____ lived, may still be lethal. can be short/long exposure. may be treated with ...

PED1003 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++ Which type of antibiotics targets the elongation phase of translation by binding to the 30s ribosomal subunit? Tetracyclines How does Tetracyclines work? Inhibit tRNA from binding In what phases are drugs tested on healthy participants rather than individuals with the condition? Phase I and II In terms of Non-adrenergic Non-cholinergic innervation of respiratory mechanisms, what is an inhibitory mediator? Nitric Ox...