BIOL3003

BIOL3003 - ADAPTIVE IMMUNITY 1 (L1) EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED CD8 T cell Cytotoxic T lymphocyte, kills virally infected cells CD4 T cell types Th1, Th2, Th17, Tfh, Treg CD4 Th1 cell function Activate infected macrophages to kill bacteria living inside macrophage (Listeria, Leishmania etc). Helps B Cells CD4 Th2 cell function Helps B cells to produce antibodies CD4 Th17 cell function neutrophil response, promote barrier integrity Tfh cell function h...

BIOL3003 - EXAM 2 CONTENT EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED Biofilms Microbial communities; attached to surface covered with a protective matrix. Four steps of biofilm formation attachment, colonization, maturation, dispersal Attachment - preconditioning: microbes lay down polysaccharides, other sugars, proteins. - Pili can mediate attachment - adherence to proteins Colonization - Quorum sensing: cell-to-cell signaling that is density dependent. - activated...

WOOTEN GENETICS TEST 4 BIOL3003 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED LATEST UPDATE The beginning of an RNA strand is called _______. Acceptor In RNA, how are bases paired? A->U G->C What type of bonding is responsible for the primary structure of a protein? Peptide Bonds If you were to break down a protein molecule, you would find that it is made up of what? Amino Acids A transition type of gene mutation is cause when....? AT is replaced by GC Why are fra...

BIOL3003 EOS STUDY TOPIC 4 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED LATEST UPDATE How do bacteria and viruses defend themselves? Bacteria use restriction enzymes to cut pathogen DNA, while viruses (mimivirus) and virophages (sputnik) engage in parasitic relationships. What immune components do invertebrates have? Invertebrates lack an acquired immune system by possess roving phagocytes, pattern recognition receptors, and antimicrobial peptide production. What are the re...

BIOL3003 WEEK 6-13 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED LATEST UPDATE What are antibodies? Glycoproteins secreted by B cells What is the difference between polyclonal and monoclonal antibodies? (Week 6 lec 16) Polyclonal: - animal immunised - serum collected - antibody is affinity purified - antibody is heterogeneous, limited supply, batch specific Monoclonal: - animal immunised - spleen cells harvested and fused with myeloma cells - single cell clones scre...

FINAL BIOL3003 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED LATEST UPDATE Function of CD8 Tcell Kill virally infected cell Functions of CD4 Th1 cell Activate macrophage and help B cells produce antibody Functions of CD4 Th2 cells Help B cells switch antibodies (especially to IgE) Functions of Th17 cells Enhance neutrophile response Promote epithelial barrier integrity Functions of TfH cells Help B cells to perform isotype switching Help B cells produce antibody CD4 ...

BIOL3003 WOOTEN GENETICS 2 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED Linkage Two or more loci (genes) tend to be inherited together Linked Genes -Loci on same chromosomes -DONT assort independently -Can be separated by crossing over & recombination Crossing Over Exchange of genetic material between 2 homo chromosomes by breakage and reunion. Recombination Unique genetic material Non sister chromatids ***20% of the time Map Units 1mu= 1% Complete Linkage Male f...

BIOL3003 MID SEM EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED Immune Cell Recruitment Rolling adhesion -> Firm Adhesion (ICAM-1 - LFA-1) -> Diapedesis (immune cell squeezes through endothelium) -> Migration (along chemokine gradient to infection site) Complement System 1. Classical: Ag:Ab complex activates = recruits inflammatory cells 2. MB-Lectin: lectin - sugars on pathogen activates = opsonisation with C3b 3. Alternative: hydrolysis of C3 lets complex bind pat...

BIOL3003 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED What are the types of conventional T cells? CD4+ and CD8+ T cells Name 3 types of unconventional T cells. Natural killer T cells (NKT), Mucosal-associated invariant T cells (MAIT), and gamma delta T cells What are the 3 signals required for T cell activation? Signal 1: specificity (antigen recognition), signal 2: co-stimulation, signal 3: cytokines Describe the pathway of T cell activation Entry through high endothelial...

BIOL3003 WEEK 1-5 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED Who was Rhazes and what did he contribute? - 865-932 - Persian philosopher and alchemist who described measles and smallpox as different diseases - Proponent of the theory that immunity is acquired - Premier physician of Islam Who was Girolamo Fracastoro and what did he contribute? - - Born in Verona, educated in Padua - Proposed the theory of acquired immunity and leader in the early theories of contagion:...