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Exam (elaborations)
MICB 4131 QUIZ 3 QUESTIONS WELL CORRECTLY LATEST UPDATE 2026
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---2May 20262025/2026A+
- MICB 4131 QUIZ 3 QUESTIONS WELL CORRECTLY LATEST UPDATE 2026 
 
steps of lectin pathway - Answers 1. MBL/ficolin binding to lectins on microbial surface 
2. Activation of MASP-1 and MASP-2 
3. MASP-2 cleaves c4 into c4a and c4b (bind to cell surface) 
4. MASP-2 cleaves c2 into c2a (binds c4b) and c2b 
5. c4bc2a is now an active c3 convertase cleaving c3 into c3b (bind to cell surface) and c3a 
costimulation for CD4 T cells includes - Answers B7 (APC) and CD28 (T cell) 
IL6 signal 3 cytokine le...
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Exam (elaborations)
MICB 4131 QUIZ 2 QUESTIONS WELLL ANSWERED LATEST UPDATE 2026
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---1May 20262025/2026A+
- MICB 4131 QUIZ 2 QUESTIONS WELLL ANSWERED LATEST UPDATE 2026 
 
TNF-alpha - Answers macrophage, NK, T cells; 
 
promotes inflammation, vasodilation 
IFN-beta - Answers All cells; induces antiviral state, increases MHC I expression 
IL-2 - Answers Tc cells; T and B cell proliferation 
IL-4 - Answers Th2 cells; promotes Th2 differentiation, isotype switch to IgE 
IL-5 - Answers TH2 cells, stimulate growth and differentiation of eosinophils 
TGF-beta - Answers T cells, macrophages; inhibits T...
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TutorJosh
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Exam (elaborations)
MICB 4131 - EXAM 2 QUIESTIONS WITH VERIFIED SOLUTIONS LATEST UPDATE 2026
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---2May 20262025/2026A+
- MICB 4131 - EXAM 2 QUIESTIONS WITH VERIFIED SOLUTIONS LATEST UPDATE 2026 
 
there is only 1 type of effector CD4 T cell - Answers false 
negative selection occurs in lymph nodes where most self antigen is found - Answers false 
positive selection is necessary to ensure your T cells can recognize foreign MHC - Answers false 
clonal expansion refers to - Answers (none of the above) 
effector T cells are - Answers antigen-experienced 
memory T cells are - Answers antigen-experienced 
B and T ...
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TutorJosh
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Exam (elaborations)
MICB 4131 EXAM 3 QUESTIONS WELL ANSWERED LATEST UPDATE 2026
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---6May 20262025/2026A+
- MICB 4131 EXAM 3 QUESTIONS WELL ANSWERED LATEST UPDATE 2026 
 
What are the three signals needed for T cell activation? - Answers 1. MHC/peptide + TCR 
2. Co stimulation 
3. Cytokine secreted by APC 
What are the two molecules involved in costimulation for T cell activation? - Answers B7.1/B7.2 engages CD28 
CD4 Th1 cells activate what type of cell? - Answers Macrophages 
What do macrophages increase expression of? - Answers CD40 and TNF receptor 
What do Th1 cells initiate if pathogens pers...
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TutorJosh
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Exam (elaborations)
MICB 4131 EXAM 4 QUESTIONS WITH CORRECT ANSWERS LATEST UPDATE 2026
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---7May 20262025/2026A+
- MICB 4131 EXAM 4 QUESTIONS WITH CORRECT ANSWERS LATEST UPDATE 2026 
 
1. Innate immunity is specific for individual pathogens, and is able to discriminate between closely related molecular structures. - Answers False 
2. Adaptive immunity recognizes a broad class of pathogens. - Answers False 
3. Toll-like receptors: - Answers A. Induce the secretion of cytokines, chemokines, and anti-microbial proteins/molecules B. Found on intracellular membranes in organelles and on the cell surface membra...
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TutorJosh
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Exam (elaborations)
MICB 4131 EXAM 2 QUESTIONS WITH VERFIED SOLUTIONS LATEST UPDATE 2026
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---1May 20262025/2026A+
- MICB 4131 EXAM 2 QUESTIONS WITH VERFIED SOLUTIONS LATEST UPDATE 2026 
 
IL-1 - Answers induction of inflammation 
IL-2 - Answers secreted by T Cells, promotes B, T, NK and AICD proliferation 
IL-4 - Answers secreted by TH2 cells, promotes differentiation of T to TH2 cells and isotype switch to IgE 
IL-5 - Answers secreted by TH2, activates and generates eosinophils 
IL-7 - Answers made by stromal cells, are required for survival of naive T and B cells 
IL-15 - Answers required for memory T...
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TutorJosh
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Exam (elaborations)
MICB 4131 EXAM 1 QUESTIONS WITH VERIFIED SOLUTIONS LATEST UPDATE 2026
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---8May 20262025/2026A+
- MICB 4131 EXAM 1 QUESTIONS WITH VERIFIED SOLUTIONS LATEST UPDATE 2026 
 
Immune system protects from disease - Answers Including heritable disorders (genetic ex. SCID), acquired disorders (infections ex HIV), aging 
How does Immune system participate in disease? - Answers Allergy, Autoimmunity, Immunopathology, Graft rejection, Graft vs host disease (GVHD) 
Observed that those exposed to cowpox were protected against smallpox, however, did not know the cause of disease, prompted the term vacci...
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TutorJosh